Article
Kinesin-8 from fission yeast: a heterodimeric, plus-end-directed motor that can couple microtubule depolymerization to cargo movement.
Molecular biology of the cell - 1 Feb 2009
Grissom Paula M, Fiedler Thomas, Grishchuk Ekaterina L, Nicastro Daniela, West Robert R, McIntosh J Richard
Abstract excerpt
Fission yeast expresses two kinesin-8s, previously identified and characterized as products of the klp5(+) and klp6(+) genes. These polypeptides colocalize throughout the vegetative cell cycle as they bind cytoplasmic microtubules during interphase, spindle microtubules, and/or kinetochores during early mitosis, and the interpolar spindle as it elongates in anaphase B. Here, we describe in vitro properties of...
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