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Analysis of the Diverse Antigenic Landscape of the Malaria Invasion Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody Clonotype

2023-10-04

Abstract excerpt

<h4>SUMMARY</h4> The highly conserved and essential Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) has emerged as the leading target for vaccines that seek to protect against the disease-causing blood-stage of malaria. However, the features of the human vaccine-induced antibody response that confer highly potent inhibition of malaria parasite invasion into red blood cells are not well defin...

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Literature Corpus work
bbfaa2f9-7e18-52cb-ac78-50ae599fce6c
DOI
10.1101/2023.10.04.560576
Open publication

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Analysis of the Diverse Antigenic Landscape of the Malaria Invasion Protein RH5 Identifies a Potent Vaccine-Induced Human Public Antibody ClonotypeDOI 10.1101/2023.10.04.560576
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