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Structural characterization of MAM01 and other cost-effective engineered monoclonal antibodies for malaria prevention

2025-08-27

Abstract excerpt

Long-lasting and effective vaccines or monoclonal antibodies (mAbs) for malaria prevention are highly beneficial for people of all ages living in malaria-endemic regions. Recently, two highly protective human mAbs AB000224 (IGHV3-49/IGLV1-40) and AB007088 (IGHV3-33/IGKV1-5), which are encoded by different germline genes, were re-engineered and renamed as MAM01 and MS-1805, respectively, to improve their half-life,...

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Identifiers and source

Literature Corpus work
22e39199-5526-530f-933f-0996fec9b763
DOI
10.1101/2025.08.24.672003
Open publication

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Structural characterization of MAM01 and other cost-effective engineered monoclonal antibodies for malaria preventionDOI 10.1101/2025.08.24.672003
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