Article

An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity

2018-04-30

Abstract excerpt

<h4>ABSTRACT</h4> Formaldehyde is a ubiquitous DNA damaging agent, with human exposures occuring from both exogenous and endogenous sources. Formaldehyde can also form DNA-protein crosslinks and is representative of other such DNA damaging agents including ionizing radiation, metals, aldehydes, chemotherapeutics, and cigarette smoke. In order to identify genetic determinants of cell proliferation in response to c...

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Literature Corpus work: 0819dad9-d20a-5622-b5f6-969be202c55a
DOI: 10.1101/310730

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