Article

Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource

2022-09-13

Abstract excerpt

Fanconi anemia (FA) is a heritable malformation, bone marrow failure and cancer predisposition syndrome that confers an exceptionally high risk of developing carcinomas arising in squamous mucosal epithelia lining the mouth, proximal esophagus, vulva and anus. The origin of these cancers is not understood, and no effective way has been identified to prevent or delay their appearance. FA-associated carcinomas are a...

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Literature Corpus work: afee2af0-8f76-5096-9ed1-e651e0d31b67
DOI: 10.1101/2022.09.11.507488

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