Article

Formaldehyde-induced toxicity causes senescence and apoptosis in BMSCs via PI3K/P53 signaling pathways

2023-07-26

Abstract excerpt

<h4>Background: </h4> Formaldehyde (FA) has been classified as a human carcinogen by the International Agency for Research on Cancer (IARC) and has toxic effects on various tissues and cells. It is reported that FA can accelerate cellular senescence in mice HT22 cells and induce the apoptosis of BALB/c mice BMSCs. Our previous study has confirmed that FA has genotoxic effects on BMSCs by the formation of DNA-prote...

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Literature Corpus work: 16edee87-4393-5b16-a75d-a28740518de3
DOI: 10.21203/rs.3.rs-3194487/v1

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