Article
Identification of critical factors of the replication stress response in human cells
2025-01-12
Abstract excerpt
High fidelity of replication is important to preserve genomic integrity and ensure healthy progeny. Perturbations of replication, also known as replication stress, is frequently observed in cancer cells and is considered a cancer cell-specific trait. Although replication stress drives genomic instability and tumor progression, it also generates a targetable cancer-specific vulnerability. In order to identify poten...
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Identifiers and source
- Literature Corpus work
- 7d9c35cc-ecb1-557c-9f01-59382c8a69c3
- DOI
- 10.1101/2025.01.12.632149