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From rest to repair: Safeguarding genomic integrity in quiescent cells

20 Aug 2024

Abstract excerpt

Quiescence is an important non-pathological state in which cells pause cell cycle progression temporarily, sometimes for decades, until they receive appropriate proliferative stimuli. Quiescent cells make up a significant proportion of the body, and maintaining genomic integrity during quiescence is crucial for tissue structure and function. While cells in quiescence are spared from DNA damage associated with DNA...

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PMID: 39167890
DOI: 10.1016/j.dnarep.2024.103752

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