Article
Navigating yeast genome maintenance with functional genomics.
Briefings in functional genomics - 1 Mar 2016
Measday Vivien, Stirling Peter C
Abstract excerpt
Maintenance of genome integrity is a fundamental requirement of all organisms. To address this, organisms have evolved extremely faithful modes of replication, DNA repair and chromosome segregation to combat the deleterious effects of an unstable genome. Nonetheless, a small amount of genome instability is the driver of evolutionary change and adaptation, and thus a low level of instability is permitted in...
Topics
- Chromosomes, Fungal
- DNA Damage
- DNA Repair
- Genes, Mating Type, Fungal
- Genome, Fungal
- Genomic Instability
- Genomics
- Loss of Heterozygosity
- Microscopy
- Mutation
- Retroelements
- Saccharomyces cerevisiae
