Article

Genomic positional conservation identifies topological anchor point (tap)RNAs linked to developmental loci

2016-04-29

Abstract excerpt

The mammalian genome is transcribed into large numbers of long noncoding RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly due to their low sequence conservation and lack of identified shared properties. Here we consider positional conservation across mammalian genomes as an indicator of functional commonality. We identify 665 conserved lncRNA promoters in mouse and human...

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Literature Corpus work: 07b117a5-4464-534b-9064-a59ed392ff8d
DOI: 10.1101/051052

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