Article

Multi-landmark alignment of genomic signals reveals conserved expression patterns across transcription start sites

2021-09-03

Abstract excerpt

The prevalent one-dimensional alignment of genomic signals to a reference landmark is a cornerstone of current methods to study transcription and its DNA-dependent processes but it is prone to mask potential relations among multiple DNA elements. We developed a systematic approach to align genomic signals to multiple locations simultaneously by expanding the dimensionality of the genomic-coordinate space. We analy...

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Literature Corpus work: e835a7f7-380c-5196-b71d-4a15f7862195
DOI: 10.1101/2021.09.02.458606

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