Article
Enhancer-gene maps in the human and zebrafish genomes using evolutionary linkage conservation
2018-01-07
Abstract excerpt
The spatiotemporal expression of genes is controlled by enhancer sequences that bind transcription factors. Identifying the target genes of enhancers remains difficult because enhancers regulate gene expression over long genomic distances. To address this, we used an evolutionary approach to build two genome-wide maps of enhancer-gene associations in the human and zebrafish genomes. Enhancers were identified using...
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Identifiers and source
- Literature Corpus work
- 371cb295-ee86-5f56-a3f0-3100c9d5afd1
- DOI
- 10.1101/244475