Article

Distinct topologically associated domains underlie regulatory logic in lymphatic endothelial cells contributing to proper cell differentiation

2025-06-17

Abstract excerpt

The activation and repression of genes is a fundamental part of proper embryonic development and functional tissue formation, ensuring that unique molecular codes are set up to orchestrate cell differentiation. Changes in chromatin organisation dictate accessibility to gene regulatory elements and control gene expression. Several molecular factors regulating lymphatic endothelial cell (LEC) specification and diffe...

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Literature Corpus work: c894129f-eae9-582d-ab86-cb29d44c0b79
DOI: 10.1101/2025.06.16.659849

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