Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cis-Acting Complex-Trait-Associated lincRNA Expression Correlates with Modulation of Chromosomal Architecture.

Cell reports - 28 Feb 2017

Tan Jennifer Yihong, Smith Adam Alexander Thil, Ferreira da Silva Maria, Matthey-Doret Cyril, Rueedi Rico, Sönmez Reyhan, Ding David, Kutalik Zoltán, Bergmann Sven, Marques Ana Claudia

Abstract excerpt

Intergenic long noncoding RNAs (lincRNAs) are the largest class of transcripts in the human genome. Although many have recently been linked to complex human traits, the underlying mechanisms for most of these transcripts remain undetermined. We investigated the regulatory roles of a high-confidence and reproducible set of 69 trait-relevant lincRNAs (TR-lincRNAs) in human lymphoblastoid cells whose biological...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Chromatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes

Share to Gene Expression

Share to Human Umbilical Vein Endothelial Cells

Share to K562 Cells

Share to Quantitative Trait Loci

Share to RNA, Long Noncoding

Source

Identifiers

PMID: 28249171
DOI: 10.1016/j.celrep.2017.02.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cis-Acting Complex-Trait-Associated lincRNA Expression Correlates with Modulation of Chromosomal Architecture.PMID 28249171Read ↗

Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs.Semantic proximity Read ↗

Genetic and epigenetic regulation of human lincRNA gene expression.Semantic proximity Read ↗

Epigenomic footprints across 111 reference epigenomes reveal tissue-specific epigenetic regulation of lincRNAs.Semantic proximity Read ↗

The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4Semantic proximity Read ↗

Comprehensive characterization genetic regulation and chromatin landscape of enhancer-associated long non-coding RNAs and their implication in human cancer.Semantic proximity Read ↗

Population Variation and Genetic Control of Modular Chromatin Architecture in Humans.Semantic proximity Read ↗

Genome-wide interrogation reveals hundreds of long intergenic noncoding RNAs that associate with cardiometabolic traits.Semantic proximity Read ↗

Many long intergenic non-coding RNAs distally regulate mRNA gene expression levelsSemantic proximity Read ↗

A Comprehensive Characterization of the Function of LincRNAs in Transcriptional Regulation Through Long-Range Chromatin Interactions.Semantic proximity Read ↗

Human disease-associated genetic variation impacts large intergenic non-coding RNA expression.Semantic proximity Read ↗

Long-range control of gene expression: emerging mechanisms and disruption in disease.Semantic proximity Read ↗

An unexpected contribution of lincRNA splicing to enhancer functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.