Article

Deep integrative models for large-scale human genomics

2021-06-11

Abstract excerpt

<h4>ABSTRACT</h4> Polygenic risk scores (PRSs) are expected to play a critical role in achieving precision medicine. Currently, PRS predictors are generally based on linear models using summary statistics, and more recently individual-level data. However, these predictors mainly capture additive relationships and are limited in data modalities they can use. Here, we developed a deep learning framework (EIR) for P...

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Literature Corpus work: 07a6e1b3-e535-547f-b135-863e4705d9e3
DOI: 10.1101/2021.06.11.447883

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