Article

A Deep Learning-based Genome-wide Polygenic Risk Score for Common Diseases Identifies Individuals with Risk

2021-11-21

Abstract excerpt

Identifying individuals at high risk in the population is a key public health need. For many common diseases, individual susceptibility may be influenced by genetic variation. Recently, the clinical potential of polygenic risk score (PRS) has attracted widespread attention. However, the performance of traditional methods is limited in fitting capabilities of the linear model and unable to capture the interaction i...

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Literature Corpus work: 32a8d255-edde-5332-a20a-864274637948
DOI: 10.1101/2021.11.17.21265352

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