Article

Investigating the role of Rts1 in DNA replication initiation

2018-03-06

Abstract excerpt

<h4>Background: </h4> Understanding DNA replication initiation is essential to understand the mis-regulation of replication seen in cancer and other human disorders. DNA replication initiates from DNA replication origins. In eukaryotes, replication is dependent on cell cycle kinases which function during S phase. Dbf4-dependent kinase (DDK) and cyclin-dependent kinase (CDK) act to phosphorylate the DNA helicase (c...

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Literature Corpus work: 07a6288d-d862-5dd7-aa71-f153999a94de
DOI: 10.12688/wellcomeopenres.13884.1

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