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Identification of novel factors involved in or regulating initiation of DNA replication by a genome-wide phenotypic screen in Saccharomyces cerevisiae.

Cell cycle (Georgetown, Tex.) - 1 Nov 2010

Ma Lijuan, Zhai Yuanliang, Feng Daorong, Chan Tsz-choi, Lu Yongjun, Fu Xinrong, Wang Jiafeng, Chen Yanhong, Li Jianna, Xu Ke, Liang Chun

Abstract excerpt

DNA replication in eukaryotic cells is tightly regulated to ensure faithful inheritance of the genetic material. While the replicators, replication origins and many replication-initiation proteins in Saccharomyces cerevisiae have been identified and extensively studied, the detailed mechanism that controls the initiation of DNA replication is still not well understood. It is likely that some factors involved in...

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PMID: 20980819
DOI: 10.4161/cc.9.21.13679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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