Article

Predicting risk of Alzheimer’s disease using polygenic risk scores developed for Parkinson’s disease

2023-08-21

Abstract excerpt

<h4>Background and Objectives</h4> The two most common neurodegenerative diseases are Alzheimer’s disease (AD) and Parkinson’s disease (PD), both related to age and affect millions of people across the world, especially as life expectancy increases in certain countries. Here, we explore the potential predictiveness of the genetic risk of AD and PD separately and then the extent of the underlying shared genetics of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 073e7db2-ca0f-58fa-88c3-50b5ba7f4142
DOI: 10.1101/2023.08.16.23294135

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predicting risk of Alzheimer’s disease using polygenic risk scores developed for Parkinson’s diseaseDOI 10.1101/2023.08.16.23294135Read

Polygenic Risk Scores Contribute to Personalized Medicine of Parkinson’s DiseaseSemantic proximity Read

Genome-Wide Polygenic Risk Score Identifies Individuals at Elevated Parkinson’s Disease RiskSemantic proximity Read

A/T/N polygenic risk score for cognitive decline in old ageSemantic proximity Read

Genetic risk in Alzheimer's disease.Semantic proximity Read

Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk.Semantic proximity Read

Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores is most accurate when using all genetic information.Semantic proximity Read

Polygenic risk score-based prediction for Parkinson’s diseaseSemantic proximity Read

Common polygenic variation enhances risk prediction for Alzheimer's disease.Semantic proximity Read

From Polygenic Scores to Precision Medicine in Alzheimer's Disease: A Systematic Review.Semantic proximity Read

Identifying individuals with high risk of Alzheimer's disease using polygenic risk scores.Semantic proximity Read

Parkinson’s disease determinants, prediction and gene-environment interactions in the UK BiobankSemantic proximity Read

Polygenic Risk Scores in Alzheimer's Disease Genetics: Methodology, Applications, Inclusion, and Diversity.Semantic proximity Read