Article

msCNVS: medium throughput single cell copy number variation sequencing with barcoded library construction free of preamplification toward clinical implementation

2024-04-02

Abstract excerpt

Single cell copy number variation sequencing (scCNV-seq) is valuable for genomic analysis of a variety of health and disease systems, yet the available methods either depend on either preamplification of the whole genome of each cell, special devices or untracable, which hinder scCNV-seq practice in clinics. Here we provide scalable multiplex scCNV-seq (msCNVS) that allows direct medium-throughput library construc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 072e86da-4e21-5060-9986-eb9902135212
DOI: 10.1101/2024.04.01.587505

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

msCNVS: medium throughput single cell copy number variation sequencing with barcoded library construction free of preamplification toward clinical implementationDOI 10.1101/2024.04.01.587505Read

SCCNV: a software tool for identifying copy number variation from single-cell whole-genome sequencingSemantic proximity Read

A benchmarking study of copy number variation inference methods using single-cell RNA-sequencing dataSemantic proximity Read

SMOOTH-seq: single-cell genome sequencing of human cells on a third-generation sequencing platform.Semantic proximity Read

HIPSD&R-seq enables scalable genomic copy number and transcriptome profilingSemantic proximity Read

scDPN for High-Throughput Single-Cell CNV Detection to Uncover Clonal Evolution During HCC RecurrenceSemantic proximity Read

Inferring copy number variation from gene expression data: methods, comparisons, and applications to oncologySemantic proximity Read

scCUTseq is a versatile framework for spatially resolved single-cell genomic analyses of intratumor heterogeneitySemantic proximity Read

Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI).Semantic proximity Read

Benchmarking scRNA-seq copy number variation callersSemantic proximity Read

Whole-genome sequencing analysis of copy number variation (CNV) using low-coverage and paired-end strategies is efficient and outperforms array-based CNV analysisSemantic proximity Read

Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates.Semantic proximity Read

Sensitivity to copy number variation analysis in single cell genomics.Semantic proximity Read