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scCUTseq is a versatile framework for spatially resolved single-cell genomic analyses of intratumor heterogeneity

2023-05-24

Abstract excerpt

<title>Abstract</title> <p>Chromosomal instability and copy number alterations (CNAs) are pervasive in human cancers. However, the exact timing and mechanism of CNA formation during carcinogenesis remain poorly understood. Here, we describe scCUTseq, an agile and robust workflow for spatially resolved single-cell CNA profiling which could be applied to characterize the CNA landscape in tumor samples. Importantly,...

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Literature Corpus work: c3691c86-53a1-5a67-978a-e6e530d337bd
DOI: 10.21203/rs.3.pex-1602/v1

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