Article

A benchmarking study of copy number variation inference methods using single-cell RNA-sequencing data

2024-09-14

Abstract excerpt

Single-cell RNA-sequencing (scRNA-seq) has emerged as a powerful tool for cancer research, enabling in-depth characterization of tumor heterogeneity at the single-cell level. Recently, scRNA-seq copy number variation (scCNV) inference methods have been developed, expanding the application of scRNA-seq to study genetic heterogeneity in cancer using transcriptomic data. However, the fidelity of these methods has not...

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Literature Corpus work: 5ea3ae88-1a7f-5a20-8ca1-438d6778cb83
DOI: 10.1101/2024.09.09.612120

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