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Article

Sensitivity to copy number variation analysis in single cell genomics.

Gene - 15 Jan 2022

Tu Jing, Zhou Yue, Tao Yuhan, Lu Na, Yang Yixuan, Lu Zuhong

Abstract excerpt

While previous studies have given some guidance, the sensitivity of copy number calling in single-cell genomics is still not comprehensive. We studied the impact of sequencing depth and other factors on single-cell copy number analysis. Sequencing Data from 26 datasets were retrieved, and 2946 single cells passed the filter. Thirty-eight single cells were independently downscaled to evaluate copy number variation...

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Identifiers

PMID: 34627941
DOI: 10.1016/j.gene.2021.145995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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