Article

Benchmarking scRNA-seq copy number variation callers

2024-12-21

Abstract excerpt

Copy number variations (CNVs), the gain or loss of genomic regions, are associated with different diseases and cancer types, where they are related to tumor progression and treatment outcome. Single cell technologies offer new possibilities to measure CNVs in individual cells, allowing to assess population heterogeneity and to delineate subclonal structures. Single cell whole-genome sequencing is considered the go...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d986134-e4b5-5271-b1ea-19a62b212632
DOI: 10.1101/2024.12.18.629083

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Benchmarking scRNA-seq copy number variation callersDOI 10.1101/2024.12.18.629083Read

A benchmarking study of copy number variation inference methods using single-cell RNA-sequencing dataSemantic proximity Read

Inferring copy number variation from gene expression data: methods, comparisons, and applications to oncologySemantic proximity Read

HapCNV: A Comprehensive Framework for CNV Detection in Low-input DNA Sequencing DataSemantic proximity Read

SCCNV: a software tool for identifying copy number variation from single-cell whole-genome sequencingSemantic proximity Read

Sensitivity to copy number variation analysis in single cell genomics.Semantic proximity Read

Robust analysis of allele-specific copy number alterations from scRNA-seq data with XCloneSemantic proximity Read

Robust analysis of allele-specific copy number alterations from scRNA-seq data with XClone.Semantic proximity Read

Benchmarking of Germline Copy Number Variant Callers from Whole Genome Sequencing Data for Clinical ApplicationsSemantic proximity Read

CNVPipe: An enhanced pipeline for accurate analysis of copy number variation from whole-genome sequencingSemantic proximity Read

msCNVS: medium throughput single cell copy number variation sequencing with barcoded library construction free of preamplification toward clinical implementationSemantic proximity Read

Copy Number Variation.Semantic proximity Read

Progress in Methods for Copy Number Variation Profiling.Semantic proximity Read