Article

Reconstructing and comparing signal transduction networks from single cell protein quantification data

2024-04-01

Abstract excerpt

<h4>Motivation</h4> Signal transduction networks regulate a multitude of essential biological processes and are frequently aberrated in diseases such as cancer. Developing a mechanistic understanding of such networks is essential to understand disease or cell population specific signaling and to design effective treatment strategies. Typically, such networks are computationally reconstructed based on systematic p...

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Literature Corpus work: f07aeb73-366c-5f35-86c9-fbf22e76193f
DOI: 10.1101/2024.03.29.587331

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