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Article

Predicting drug response from single-cell expression profiles of tumours

1 Dec 2023

Abstract excerpt

BACKGROUND: Intra-tumour heterogeneity (ITH) presents a significant obstacle in formulating effective treatment strategies in clinical practice. Single-cell RNA sequencing (scRNA-seq) has evolved as a powerful instrument for probing ITH at the transcriptional level, offering an unparalleled opportunity for therapeutic intervention. RESULTS: Drug response prediction at the single-cell level is an emerging field of...

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PMID: 38041118
DOI: 10.1186/s12916-023-03182-1

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