Article

An In-silico Analysis of OGT gene association with diabetes mellitus

2023-07-05

Abstract excerpt

O-GlcNAcylation is a nutrient-sensing post-translational modification process. This cycling process involves two main proteins; the O-linked N-acetylglucosamine transferase (OGT) catalyzing the addition, and the glycoside hydrolase OGA (O-GlcNAcase) catalyzing the removal of the O-GlCNAc moiety on nucleocytoplasmic proteins. This process is necessary for various important cellular functions. The O-linked N-acetylg...

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Literature Corpus work: 048e0224-bcb2-5581-bf61-ede3feb6bd7f
DOI: 10.21203/rs.3.rs-3068800/v1

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