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Article

Mutations in Glycosyltransferases and Glycosidases: Implications for Associated Diseases.

Biomolecules - 19 Apr 2024

Gu Xiaotong, Kovacs Aaron S, Myung Yoochan, Ascher David B

Abstract excerpt

Glycosylation, a crucial and the most common post-translational modification, coordinates a multitude of biological functions through the attachment of glycans to proteins and lipids. This process, predominantly governed by glycosyltransferases (GTs) and glycoside hydrolases (GHs), decides not only biomolecular functionality but also protein stability and solubility. Mutations in these enzymes have been...

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Identifiers

PMID: 38672513
DOI: 10.3390/biom14040497
PMCID: PMC11048727

Genes

MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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