Article
OGG1 Mutations and Risk of Female Breast Cancer: Meta-Analysis and Experimental Data.
Disease markers - 1 Jan 2015
Ali Kashif, Mahjabeen Ishrat, Sabir Maimoona, Mehmood Humera, Kayani Mahmood Akhtar
Abstract excerpt
In first part of this study association between OGG1 polymorphisms and breast cancer susceptibility was explored by meta-analysis. Second part of the study involved 925 subjects, used for mutational analysis of OGG1 gene using PCR-SSCP and sequencing. Fifteen mutations were observed, which included five intronic mutations, four splice site mutations, two 3'UTR mutations, three missense mutations, and a nonsense...
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