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An in silico approach to characterize nonsynonymous SNPs and regulatory SNPs in human TOX3 gene.

Journal of genetics - 1 Dec 2019

Akhtar Mehran, Jamal Tazkira, Din Jalal Ud, Hayat Chandni, Rauf Mamoona, Ul Haq Syed Manzoor, Sher Khan Raham, Shah Aftab Ali, Jamal Muhsin, Jalil Fazal

Abstract excerpt

Cancer is one of the deadliest complex diseases having multigene nature where the role of single-nucleotide polymorphism (SNP) has been well explored in multiple genes. TOX high mobility group box family member 3 (TOX3) is one such gene, in which SNPs have been found to be associated with breast cancer. In this study, we have examined the potentially damaging nonsynonymous SNPs(nsSNPs) in TOX3 gene using in...

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PMID: 31819019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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