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Article

In vitro and in silico analysis of three variants associated with type 2 diabetes.

Acta diabetologica - 1 Jul 2026

Rezaei Seyyed Amin Seyyed, Kohkalani Moein, Mehri Maghsoud, Derakhshan Sima Mansoori, Zanchi Fernando Berton, Caceres Rafael Andrade, Amirfiroozi Akbar

Abstract excerpt

BACKGROUND: Common regulatory and coding variants may influence type 2 diabetes (T2D) risk by altering gene regulation or protein function. Identifying these variants and their associations with disease risk may inform disease control strategies. This study prioritized candidate variants by integrating two-group comparative genotyping with in-silico structural and dynamic analyses. METHODS: Three prioritized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42089960
DOI: 10.1007/s00592-026-02689-2

Genes

SLC39A11
TF
TPCN2
EGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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