Article

Germline-mediated ubiquitous recombination in ScxCre male mice: implications for tendon research

2026-04-21

Abstract excerpt

Scleraxis (Scx), a basic helix-loop-helix (bHLH) transcription factor, is a primary marker for tendon and ligament lineages. Consequently, mouse models utilizing Cre recombinase under the control of the Scx locus represents a powerful tool for control of gene expression in tendon. The constitutive ScxCre mouse line is widely used for tendon-specific genetic manipulation. In this study, we demonstrate that ScxCre e...

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Literature Corpus work: 038c227b-648f-5e20-8d97-11c3d38b717e
DOI: 10.64898/2026.04.16.719028

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