Article
A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombination.
Genesis (New York, N.Y. : 2000) - 1 May 2004
Ramirez Angel, Page Angustias, Gandarillas Alberto, Zanet Jennifer, Pibre Sophie, Vidal Miguel, Tusell Laura, Genesca Anna, Whitaker Duncan A, Melton David W, Jorcano Jose L
Abstract excerpt
We describe here a mouse line bearing a bovine keratin K5Cre recombinase transgene. These mice showed a dual pattern of Cre-mediated recombination, depending on the parent transmitting the transgene. In paternal transmission, recombination occurred specifically in the skin and stratified epithelia-as expected according to the expression of endogenous keratin K5. However, constitutive recombination between loxP...
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