Article
An X-linked Myh11-CreERT2 mouse line resulting from Y to X chromosome-translocation of the Cre allele.
Genesis (New York, N.Y. : 2000) - 1 Sept 2017
Liao Mingmei, Zhou Junmei, Wang Fen, Ali Yasmin H, Chan Kelvin L, Zou Fei, Offermanns Stefan, Jiang Zhisheng, Jiang Zhihua
Abstract excerpt
The Myh11-CreERT2 mouse line (Cre+ ) has gained increasing application because of its high lineage specificity relative to other Cre drivers targeting smooth muscle cells (SMCs). This Cre allele, however, was initially inserted into the Y chromosome (X/YCre+ ), which excluded its application in female mice. Our group established a Cre+ colony from male ancestors. Surprisingly, genotype screening identified female...
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