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Article

Novel roles for scleraxis in regulating adult tenocyte function

7 Aug 2018

Abstract excerpt

BACKGROUND: Tendinopathies are common and difficult to resolve due to the formation of scar tissue that reduces the mechanical integrity of the tissue, leading to frequent reinjury. Tenocytes respond to both excessive loading and unloading by producing pro-inflammatory mediators, suggesting that these cells are actively involved in the development of tendon degeneration. The transcription factor scleraxis (Scx)...

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PMID: 30086712
DOI: 10.1186/s12860-018-0166-z

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