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Induced pluripotent stem cell-derived tenocyte-like cells promote the regeneration of injured tendons in mice

4 Mar 2020

Abstract excerpt

Tendons are dense fibrous structures that attach muscles to bones. Healing of tendon injuries is a clinical challenge owing to poor regenerative potential and scarring. Here, we created reporter mice that express EGFP, driven by the promoter of the tendon-specific Scleraxis (Scx) transcription-factor gene; we then generated induced pluripotent stem cells (iPSCs) from these mice. Utilising these fluorescently...

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PMID: 32132649
DOI: 10.1038/s41598-020-61063-6

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