Article

A New Functional F-Statistic for Gene-Based Inference Involving Multiple Phenotypes

2021-05-28

Abstract excerpt

Genetic pleiotropy is the phenomenon where a single gene or genetic variant influences multiple traits. Numerous statistical methods exist for testing for genetic pleiotropy at the variant level, but fewer methods are available for testing genetic pleiotropy at the gene-level. In the current study, we derive an exact alternative to the Shen and Faraway functional F-statistic for functional-on-scalar regression mod...

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Literature Corpus work: 0330e915-a899-505d-8e2f-20444a5d75b2
DOI: 10.1101/2021.05.28.21257997

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