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Antisense pairing and SNORD13 structure guide RNA cytidine acetylation

2022-05-13

Abstract excerpt

N4-acetylcytidine (ac 4 C) is an RNA nucleobase found in all domains of life. Establishment of ac 4 C in helix 45 (h45) of human 18S ribosomal RNA (rRNA) requires the combined activity of the acetyltransferase NAT10 and the box C/D snoRNA SNORD13. However, the molecular mechanisms governing RNA-guided nucleobase acetylation in humans remain unexplored. Here we report two assays that enable the study of SNORD13-d...

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Identifiers and source

Literature Corpus work
031899b7-9aae-5f87-90a1-df853a273039
DOI
10.1101/2022.05.12.491732
Open publication

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Antisense pairing and SNORD13 structure guide RNA cytidine acetylationDOI 10.1101/2022.05.12.491732
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