Article

Mapping targets for small nucleolar RNAs in yeast

2018-11-22

Abstract excerpt

<h4>Background: </h4> Recent analyses implicate changes in the expression of the box C/D class of small nucleolar RNAs (snoRNAs) in several human diseases. <h4>Methods: </h4>: Here we report the identification of potential novel RNA targets for box C/D snoRNAs in budding yeast, using the approach of UV crosslinking and sequencing of hybrids (CLASH) with the snoRNP proteins Nop1, Nop56 and Nop58. We also developed...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 700a6fc3-b173-58e7-8b3a-e96627fa761a
DOI: 10.12688/wellcomeopenres.14735.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mapping targets for small nucleolar RNAs in yeastDOI 10.12688/wellcomeopenres.14735.2Read

Systematic mapping of small nucleolar RNA targets in human cellsSemantic proximity Read

High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seqSemantic proximity Read

RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability.Semantic proximity Read

Human NOP2/NSUN1 Regulates Ribosome Biogenesis Through Non-Catalytic Complex Formation with Box C/D snoRNPsSemantic proximity Read

Interprotomer Communication and Functional Asymmetry in H/ACA snoRNPsSemantic proximity Read

SnoRNA guide activities – real and ambiguousSemantic proximity Read

Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathways.Semantic proximity Read

Individual nucleotide resolution UV cross-linking and immunoprecipitation (iCLIP) to determine protein-RNA interactionsSemantic proximity Read

Functional base-pairing interaction between highly conserved elements of U3 small nucleolar RNA and the small ribosomal subunit RNA.Semantic proximity Read

RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationshipsSemantic proximity Read

Rrp8p is a yeast nucleolar protein functionally linked to Gar1p and involved in pre-rRNA cleavage at site A2.Semantic proximity Read

MRE11-RAD50-NBS1 activates Fanconi Anemia R-loop suppression at transcription-replication conflictsSemantic proximity Read