Article

EOLA1 functions in nucleotide salvage through deacetylating free N4-acetylcytidine

2026-08-04

Abstract excerpt

<h4>Summary</h4> RNA-based medicines rely on modified nucleotides to promote immune evasion and in vivo efficacy. Nucleotides generated from RNA degradation are either exported or recycled through metabolically favorable salvage pathways, though whether modified nucleotides are efficiently recycled remains unclear. N 4 -acetylcytidine (ac⁴C) is a naturally occurring modification in rRNA and tRNA that has shown p...

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Literature Corpus work: 695d2973-969f-5755-a97a-77c049c8cd6d
DOI: 10.64898/2026.08.01.741249

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