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Research progress on NAT10-mediated acetylation in normal development and disease

13 Aug 2025

Abstract excerpt

N4-acetylcytidine (ac4C) is an evolutionarily conserved RNA modification catalyzed by the acetyltransferase NAT10. It regulates RNA stability, translation, and post-transcriptional processes. Meanwhile, NAT10 functions as a dual-function enzyme exhibiting both protein acetyltransferase and RNA acetylase activities. This review summarizes the structural and functional roles of NAT10-mediated acetylation in...

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PMID: 40881352
DOI: 10.3389/fcell.2025.1623276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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