Article

Spatially resolved transcriptomic and proteomic profiling reveals cell interaction programs that predict Barrett’s esophagus progression

2026-05-12

Abstract excerpt

Barrett’s esophagus (BE) is the precursor lesion of esophageal adenocarcinoma (EAC). It affects approximately 5% of adults in the United States and significantly increases the risk of developing EAC. However, current surveillance strategies cannot reliably distinguish patients who will progress from those who will remain stable. Direct studies of progressor BE are extremely limited due to availability of tissue wi...

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Literature Corpus work: 02deaad4-a010-5386-a998-e236866499af
DOI: 10.64898/2026.05.08.723546

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