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Histopathology-based Spatial Profiling of Immune and Molecular Features Predicts Cancer risk in Barrett’s Esophagus

2025-11-13

Abstract excerpt

<h4>Background</h4> Improved cancer risk stratification is needed to differentiate high-risk individuals with Barrett’s esophagus (BE) from low-risk populations to reduce overtreatment and improve outcome. The evolution of BE towards adenocarcinoma is likely driven by a combination of genomic and microenvironmental factors, yet existing predictive models rarely integrate both using routine specimens. <h4>Method</...

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Literature Corpus work
31f34b22-7d8f-5c37-8931-6f748f14b05e
DOI
10.1101/2025.11.11.25339952
Open publication

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Histopathology-based Spatial Profiling of Immune and Molecular Features Predicts Cancer risk in Barrett’s EsophagusDOI 10.1101/2025.11.11.25339952
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