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Article

Alterations of the composition and spatial organization of the microenvironment following non-dysplastic Barrett’s esophagus through progression to cancer

2025-06-12

Abstract excerpt

Barrett’s esophagus (BE), a metaplastic condition that is the only known precursor for esophageal adenocarcinoma (EAC), is relatively common, but progression to cancer is infrequent. BE is inflamed but the contribution of the immune system to the carcinogenic process is unknown. To this end, we contrasted non-dysplastic metaplasia of BE patients, captured when they did not progress (non-progressors), did subsequen...

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Literature Corpus work
e6d1e737-5f18-5b09-9c64-1aa0960dbd34
DOI
10.1101/2025.06.09.657642
Open publication

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Alterations of the composition and spatial organization of the microenvironment following non-dysplastic Barrett’s esophagus through progression to cancerDOI 10.1101/2025.06.09.657642
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