Back to search

Article

Transcriptomic Changes and Biomarkers in Barrett's Metaplasia, Dysplasia and Cancer

2026-08-25

Abstract excerpt

Esophageal adenocarcinoma (EAC) has a poor five-year survival rate and one of the fastest-rising incidences of any cancer. The presence of dysplasia in Barrett's esophagus (BE) is the main risk factor for EAC development and guides clinical management. Unfortunately, the current histopathological diagnosis of dysplasia is unreliable, with poor inter-observer agreement, highlighting the need for novel biomarkers th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
eb8c5b0b-a5e4-53a9-a726-8483a5795d3c
DOI
10.64898/2026.08.25.746910
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transcriptomic Changes and Biomarkers in Barrett's Metaplasia, Dysplasia and CancerDOI 10.64898/2026.08.25.746910
Novel Aberrations Uncovered in Barrett's Esophagus and Esophageal Adenocarcinoma Using Whole Transcriptome Sequencing.Semantic proximity
Overview of major molecular alterations during progression from Barrett's esophagus to esophageal adenocarcinomaSemantic proximity
EsoDetect: Computational Validation and Algorithm Development of a Novel Diagnostic and Prognostic Tool for Dysplasia in Barrett’s EsophagusSemantic proximity
Development of a Diagnostic Model for Barrett's Esophagus and Esophageal Adenocarcinoma Based on Machine Learning and Immune InfiltrationSemantic proximity
Molecular Abnormalities and Carcinogenesis in Barrett’s Esophagus: Implications for Cancer Treatment and PreventionSemantic proximity
Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” eraSemantic proximity
Concerted epithelial and stromal changes during progression of Barrett’s Esophagus to invasive adenocarcinoma exposed by multi-scale, multi-omics analysisSemantic proximity
A multigene expression panel for the molecular diagnosis of Barrett's esophagus and Barrett's adenocarcinoma of the esophagusSemantic proximity
Predicting the Risk of Progression from Barrett’s Esophagus to Esophageal Adenocarcinoma with a Mass-Spectrometry-Based Proteomic PanelSemantic proximity
Expression Analysis of Barrett's Esophagus–Associated High-Grade Dysplasia in Laser Capture Microdissected Archival TissueSemantic proximity
Genomic similarity between gastroesophageal junction and esophageal Barrett's adenocarcinomas.Semantic proximity
A comprehensive analysis of single-cell transcriptome network underlying gastric premalignant lesions and early gastric cancerSemantic proximity
Select a neighboring publication to make it the new centre.