Article

V <sub>0</sub> -ATPase downregulation induces MVID-like brush border defects independently of apical trafficking in the mammalian intestine

2022-11-04

Abstract excerpt

<h4>Summary</h4> Intestinal microvillus atrophy is a major cause of enteropathies such as idiopathic or congenital diarrhea that are often associated with severe morbidity. It can be caused by genetic disorders, inflammatory diseases, toxins or pathogens. In particular, Microvillus inclusion disease (MVID) is characterized by a chronic intractable diarrhea and a severe microvillus atrophy. It is triggered by muta...

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Literature Corpus work: 01bc01aa-7f40-5600-b6fb-cb11e024dc60
DOI: 10.1101/2022.11.04.515188

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