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Article

The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans.

The Journal of cell biology - 19 Jun 2006

Liégeois Samuel, Benedetto Alexandre, Garnier Jean-Marie, Schwab Yannick, Labouesse Michel

Abstract excerpt

Polarized intracellular trafficking in epithelia is critical in development, immunity, and physiology to deliver morphogens, defensins, or ion pumps to the appropriate membrane domain. The mechanisms that control apical trafficking remain poorly defined. Using Caenorhabditis elegans, we characterize a novel apical secretion pathway involving multivesicularbodies and the release of exosomes at the apical plasma...

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Identifiers

PMID: 16785323
DOI: 10.1083/jcb.200511072
PMCID: PMC2063919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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