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The zebrafish <i>goosepimples/myosin Vb</i> mutant exhibits cellular attributes of human microvillus inclusion disease

2015-11-03

Abstract excerpt

Background: Microvillus inclusion disease (MVID) is a life threatening enteropathy characterised by perpetual diarrhoea. Recent analysis has revealed that enterocytes in MVID patients exhibit reduction of microvilli, presence of microvillus inclusion bodies and intestinal villus atrophy. Genetic linkage analysis has identified mutations in myosin Vb gene as the main cause of MVID. An animal model that develops ex...

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Literature Corpus work
7610b1af-9602-5e08-8d77-ba2176e08e87
DOI
10.1101/030536
Open publication

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The zebrafish <i>goosepimples/myosin Vb</i> mutant exhibits cellular attributes of human microvillus inclusion diseaseDOI 10.1101/030536
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