Article

A V0-ATPase-dependent apical trafficking pathway maintains the polarity of the intestinal absorptive membrane

2018-09-08

Abstract excerpt

Intestine function relies on the strong polarity of intestinal epithelial cells and the array of microvilli forming a brush border at their luminal pole. Combining genetic RNAi screen and in vivo super-resolution imaging in the C . elegans intestine, we uncovered that the V0 sector of the V-ATPase (V0-ATPase) controls a late apical trafficking step, involving RAB-11 endosomes and the SNARE SNAP-29, necessary to...

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Literature Corpus work: bbe09b49-bfe4-5629-9ac4-cce3a92aafd4
DOI: 10.1101/412122

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