Article

Hierarchy and networks in the transcriptional response of <i>Mycobacterium abscessus</i> to antibiotics

2023-03-17

Abstract excerpt

Mycobacterium abscessus causes acute and chronic pulmonary infection in patients with chronic lung damage. It is intrinsically resistance to antibiotics effective against other pathogenic mycobacteria largely due to the drug-induced expression of genes that confer resistance. Induction of genes upon exposure to ribosome targeting antibiotics proceeds via WhiB7-dependent and -independent pathways. WhiB7 controls th...

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Literature Corpus work: 01646b12-d4b5-57bb-ab3a-e8ea38bb4693
DOI: 10.1101/2023.03.16.533064

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